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Management of perioperative anticoagulation in a patient with antiphospholipid antibody syndrome undergoing cardiac surgery: A case report


Baylor College of Medicine, Houston, Texas, USA

Correspondence Address:
Sanjana A Malviya
One Baylor Plaza MS BCM: 120, Neurosensory Building, Houston, TX 77030
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aca.aca_228_20

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Year : 2022  |  Volume : 25  |  Issue : 2  |  Page : 206-209

 

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Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.






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Baylor College of Medicine, Houston, Texas, USA

Correspondence Address:
Sanjana A Malviya
One Baylor Plaza MS BCM: 120, Neurosensory Building, Houston, TX 77030
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aca.aca_228_20

Rights and Permissions

Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.






[FULL TEXT] [PDF]*


        
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